Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazole

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Prevention and treatment of Encephalitozoon cuniculi infection in immunosuppressed rabbits with fenbendazole

This study was conducted to evaluate the efficacy of oral administration of fenbendazole (20 mg/kg body weight) prior to and after experimental infection of immunosuppressed rabbits with Encephalitozoon cuniculi. A total of thirty rabbits were divided into five groups: NN (non-immunosuppressed; non-infected), IN (immunosuppressed; non-infected), IPI (immunosuppressed; protected-infected), ITI (...

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Prevention and treatment of Encephalitozoon cuniculi infection in rabbits with fenbendazole.

The efficacy of fenbendazole for preventing an experimental infection of Encephalitozoon cuniculi and for eliminating the spores from the central nervous system of naturally infected rabbits was investigated. Fenbendazole (20 mg/kg bodyweight daily) was administered from seven days before until two or 21 days after rabbits had been infected orally with 10(6) spores of E. cuniculi. Both regimens...

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Prevention and treatment of Encephalitozoon cuniculi infection in immunosuppressed rabbits with fenbendazole.

This study was conducted to evaluate the efficacy of oral administration of fenbendazole (20 mg/kg body weight) prior to and after experimental infection of immunosuppressed rabbits with Encephalitozoon cuniculi. A total of thirty rabbits were divided into five groups: NN (non-immunosuppressed; non-infected), IN (immunosuppressed; non-infected), IPI (immunosuppressed; protected-infected), ITI (...

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Encephalitozoon cuniculi Infection in Rabbits

intracellular parasite in the phylum Microspora, which is defined by its resistant spore stage. Microsporidia receive little attention in veterinary medical curricula because they are considered important only as parasites of rabbits and fish. Microsporidia are important parasites of humans as well, with some species causing severe disease and death in immunocompromised individuals. Microsporid...

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Altered immune responsiveness associated with Encephalitozoon cuniculi infection in rabbits.

The variation in immune response of two unrelated colonies of laboratory rabbits to high doses of heat-killed Brucella abortus strain 19 was investigated. One was a mixed-breed, multicolored colony in which a high prevalence of encephalitozoonosis had been recorded, whereas the other rabbits were derived from a colony of Dutch-marked specific-pathogen-free rabits. Although considerable variatio...

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ژورنال

عنوان ژورنال: Veterinary Record

سال: 2001

ISSN: 0042-4900

DOI: 10.1136/vr.148.15.478